• CD272 Polyclonal Antibody
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Upingbio

YP-Ab-13890-100UL

CD272 Polyclonal Antibody

CD272 Polyclonal Antibody

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  • Gene Name: BTLA
  • Immunogen: Synthetic peptide from human protein at AA range: 101-150
  • Specificity: CD272 Polyclonal Antibody detects endogenous levels of CD272 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: BTLA; B- and T-lymphocyte attenuator; B- and T-lymphocyte-associated protein; CD antigen CD272
  • Background: This gene encodes a member of the immunoglobulin superfamily. The encoded protein contains a single immunoglobulin (Ig) domain and is a receptor that relays inhibitory signals to suppress the immune response. Alternative splicing results in multiple transcript variants. Polymorphisms in this gene have been associated with an increased risk of rheumatoid arthritis. [provided by RefSeq, Aug 2011],
  • Function: function:Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response.,PTM:N-glycosylated.,PTM:Phosphorylated on Tyr residues by TNFRSF14 and by antigen receptors cross-linking, both inducing association with PTPN6 and PTPN11.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Interacts with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2. Interacts with TNFRSF14/HVEM.,
  • Species: Human;Rat;Mouse;
  • Range: WB;IHC;IF;FCM;ELISA
  • Protein: B- and T-lymphocyte attenuator
  • DA: 36kD
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