• CD160 Polyclonal Antibody
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Upingbio

YP-Ab-13882-100UL

CD160 Polyclonal Antibody

CD160 Polyclonal Antibody

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  • Gene Name: CD160
  • Immunogen: The antiserum was produced against synthesized peptide derived from human CD160. AA range:21-70
  • Specificity: CD160 Polyclonal Antibody detects endogenous levels of CD160 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: CD160; BY55; CD160 antigen; Natural killer cell receptor BY55; CD antigen CD160
  • Background: CD160 is an 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. C
  • Function: function:Receptor showing broad specificity for both classical and non-classical MHC class I molecules.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Homomultimer; disulfide-linked.,tissue specificity:Expressed in spleen, peripheral blood, and small intestine. Expression is restricted to functional NK and T cytotoxic lymphocytes.,
  • Species: Human;Rat;Mouse;
  • Range: WB;IF;ELISA
  • Protein: CD160 antigen
  • DA: 17kD
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