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Upingbio
SKU:YP-Ab-13830-10UL
Kif 7 Monoclonal Antibody(3F8)
Kif 7 Monoclonal Antibody(3F8)
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- Reaction species: Human;Mouse;Rat
- Gene Name: KIF7
- Protein name: Kinesin-like protein KIF7
- Immunogen: Synthetic Peptide of Kif 7
- Specificity: The antibody detects endogenous Kif 7 proteins.
- Composition: PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
- Source: Monoclonal, Mouse
- Dilution ratio: WB 500-2000 1:200 IF 1:50-200
- Purification process: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
- Storage: -20°C/1 year
- Other Names: Kinesin-like protein KIF7
- Background: This gene encodes a cilia-associated protein belonging to the kinesin family. This protein plays a role in the sonic hedgehog (SHH) signaling pathway through the regulation of GLI transcription factors. It functions as a negative regulator of the SHH pathway by preventing inappropriate activation of GLI2 in the absence of ligand, and as a positive regulator by preventing the processing of GLI3 into its repressor form. Mutations in this gene have been associated with various ciliopathies. [provided by RefSeq, Oct 2011],
- Function: similarity:Belongs to the kinesin-like protein family. KIF27 subfamily.,similarity:Contains 1 kinesin-motor domain.,tissue specificity:Embryonic stem cells, melanotic melanoma and Jurkat T-cells.,
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