• CD14 Monoclonal Antibody
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Upingbio

YP-Ab-13787-53UL

CD14 Monoclonal Antibody

CD14 Monoclonal Antibody

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  • Reaction species: Human
  • Gene Name: CD14
  • Protein name: Monocyte differentiation antigen CD14
  • Immunogen: Purified recombinant fragment of human CD14 expressed in E. Coli.
  • Specificity: CD14 Monoclonal Antibody detects endogenous levels of CD14 protein.
  • Composition: Purified antibody in PBS containing 0.03% sodium azide.
  • Source: Monoclonal, Mouse
  • Dilution ratio: IHC: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: 1/10000.. IF 1:50-200
  • Purification process: Affinity purification
  • Concentration: mg/ml
  • Storage: -20°C/1 year
  • Other Names: CD14; Monocyte differentiation antigen CD14; Myeloid cell-specific leucine-rich glycoprotein; CD antigen CD14
  • Background: The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Mar 2010],
  • Function: function:Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.,online information:CD14 entry,similarity:Contains 11 LRR (leucine-rich) repeats.,subunit:Belongs to the lipopolysaccharide (LPS) receptor, a multi-protein complex containing at least CD14, MD-2 and TLR4.,tissue specificity:Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages.,
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