• EMR2 (Cleaved-Leu517) rabbit pAb
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YP-Ab-13782-100UL

EMR2 (Cleaved-Leu517) rabbit pAb

EMR2 (Cleaved-Leu517) rabbit pAb

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  • Gene Name: EMR2
  • Immunogen: Synthesized peptide derived from human EMR2 (Cleaved-Leu517)
  • Specificity: This antibody detects endogenous levels of Human EMR2 (Cleaved-Leu517, protein was cleaved amino acid sequence between 517-518 )
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:1000-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: EGF-like module-containing mucin-like hormone receptor-like 2 (EGF-like module receptor 2;CD antigen CD312)
  • Background: This gene encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors. These proteins are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor-like domains coupled to a TM7 domain via a mucin-like spacer domain. The encoded protein is expressed mainly in myeloid cells where it promotes cell-cell adhesion through interaction with chondroitin sulfate chains. This gene is situated in a cluster of related genes on chromosome 19. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012],
  • Function: alternative products:A number of isoforms are produced. A number of isoforms consisting of various number of EGF-like domains seems to exist. A soluble form due to a frameshift which introduced a stop codon immediately before the first TM domain is also detected,domain:Binding to chondroitin sulfate is mediated by the fourth EGF domain.,domain:The GPS domain is necessary, but not sufficient for receptor cleavage, which require the entire extracellular stalk.,function:Receptor probably involved in cell attachment.,PTM:Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,similarity:Contains 5 EGF-like domains.,subunit:Forms a heterodimer, consisting of a large extracellular region non-covalently linked to a seven-transmembr
  • Species: Human
  • Range: WB; ELISA
  • Protein: EMR2 (Cleaved-Leu517)
  • DA: 57kD
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