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Upingbio
SKU:YP-Ab-13761-100UL
CD168 Polyclonal Antibody
CD168 Polyclonal Antibody
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- Gene Name: HMMR IHABP RHAMM
- Immunogen: Synthetic peptide from human protein at AA range: 280-340
- Specificity: The antibody detects endogenous CD168
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000. IF 1:50-200
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: Hyaluronan mediated motility receptor (Intracellular hyaluronic acid-binding protein;Receptor for hyaluronan-mediated motility;CD antigen CD168)
- Background: The protein encoded by this gene is involved in cell motility. It is expressed in breast tissue and together with other proteins, it forms a complex with BRCA1 and BRCA2, thus is potentially associated with higher risk of breast cancer. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Dec 2008],
- Function: function:Involved in cell motility. When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including the focal adhesion kinase occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity.,subunit:Subunit of the HARC complex.,tissue specificity:Expressed in breast cancer cell lines and in normal breast tissue.,
- Species: Human;Rat;Mouse;
- Range: WB;IHC;IF;ELISA
- Protein: Hyaluronan mediated motility receptor (Intracellular hyaluronic acid-binding protein) (Receptor for hyaluronan-mediated motility) (CD antigen CD168)
- DA: 84kD
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