• EP1 Polyclonal Antibody
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Upingbio

YP-Ab-13733-100UL

EP1 Polyclonal Antibody

EP1 Polyclonal Antibody

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  • Gene Name: PTGER1
  • Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human PTGER1. AA range:191-240
  • Specificity: EP1 Polyclonal Antibody detects endogenous levels of EP1 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: PTGER1; Prostaglandin E2 receptor EP1 subtype; PGE receptor EP1 subtype; PGE2 receptor EP1 subtype; Prostanoid EP1 receptor
  • Background: The protein encoded by this gene is a member of the G protein-coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). Through a phosphatidylinositol-calcium second messenger system, G-Q proteins mediate this receptor's activity. Knockout studies in mice suggested a role of this receptor in mediating algesia and in regulation of blood pressure. Studies in mice also suggested that this gene may mediate adrenocorticotropic hormone response to bacterial endotoxin. [provided by RefSeq, Jul 2008],
  • Function: function:Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues.,PTM:Phosphorylated .,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Abundant in kidney. Lower level expression in lung, skeletal muscle and spleen, lowest expression in testis and not detected in liver brain and heart.,
  • Species: Human;Rat;Mouse;
  • Range: WB;ELISA
  • Protein: Prostaglandin E2 receptor EP1 subtype
  • DA: 44kD
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