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SKU:YP-Ab-13681-100UL
T2R16 Polyclonal Antibody
T2R16 Polyclonal Antibody
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- Gene Name: TAS2R16
- Immunogen: The antiserum was produced against synthesized peptide derived from human TAS2R16. AA range:136-185
- Specificity: T2R16 Polyclonal Antibody detects endogenous levels of T2R16 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: TAS2R16; Taste receptor type 2 member 16; T2R16
- Background: This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily. These family members are specifically expressed by taste receptor cells of the tongue and palate epithelia. Each of these apparently intronless genes encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered with another 3 candidate taste receptor genes in chromosome 7 and is genetically linked to loci that influence bitter perception. [provided by RefSeq, Jul 2008],
- Function: function:Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.,miscellaneous:Confers bitter perception of salicin to non-taster mice.,miscellaneous:Several bitter taste receptors are expressed in a single taste receptor cell.,polymorphism:The Lys-172 polymorphism in TAS2R16 is associated with genetic susceptibility to alcoholism [MIM:103780].,similarity:Belongs to the G-protein coupled receptor T2R family.,tissue specificity:Expressed in a subset of gustducin-positive taste receptor cells of the tongue.,
- Species: Human;Rat;Mouse;
- Range: WB;IF;ELISA
- Protein: Taste receptor type 2 member 16
- DA: 34kD
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