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Upingbio

SKU:YP-Ab-13677-100UL

T2R1 Polyclonal Antibody

T2R1 Polyclonal Antibody

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  • Gene Name: TAS2R1
  • Immunogen: The antiserum was produced against synthesized peptide derived from human TAS2R1. AA range:6-55
  • Specificity: T2R1 Polyclonal Antibody detects endogenous levels of T2R1 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: TAS2R1; Taste receptor type 2 member 1; T2R1; Taste receptor family B member 7; TRB7
  • Background: This gene encodes a member of a family of candidate taste receptors that are members of the G protein-coupled receptor superfamily and that are specifically expressed by taste receptor cells of the tongue and palate epithelia. This intronless taste receptor gene encodes a 7-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is mapped to chromosome 5p15, the location of a genetic locus (PROP) that controls the detection of the bitter compound 6-n-propyl-2-thiouracil. [provided by RefSeq, Jul 2008],
  • Function: function:Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.,miscellaneous:Most taste cells may be activated by a limited number of bitter compounds; individual taste cells can discriminate among bitter stimuli.,similarity:Belongs to the G-protein coupled receptor T2R family.,tissue specificity:Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin-positive cells.,
  • Species: Human;Rat;Mouse;
  • Range: WB;ELISA;IHC
  • Protein: Taste receptor type 2 member 1
  • DA: 33kD
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