• Rhodopsin Polyclonal Antibody
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Upingbio

YP-Ab-13671-100UL

Rhodopsin Polyclonal Antibody

Rhodopsin Polyclonal Antibody

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  • Gene Name: RHO
  • Immunogen: The antiserum was produced against synthesized peptide derived from human Rhodopsin. AA range:299-348
  • Specificity: Rhodopsin Polyclonal Antibody detects endogenous levels of Rhodopsin protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/100 - 1/300. ELISA: 1/5000.. IF 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: RHO; OPN2; Rhodopsin; Opsin-2
  • Background: Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25% of total cases, approximately 30% of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness. [provided by RefSeq, Jul 2008],
  • Function: disease:Defects in RHO are a cause of retinitis pigmentosa autosomal recessive (ARRP) [MIM:268000].,disease:Defects in RHO are the cause of congenital stationary night blindness autosomal dominant type 1 (CSNBAD1) [MIM:610445]; also known as rhodopsin-related congenital stationary night blindness. Congenital stationary night blindness is a non-progressive retinal disorder characterized by impaired night vision.,disease:Defects in RHO are the cause of retinitis pigmentosa type 4 (RP4) [MIM:180380]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well. RP4 inheritance is autosomal dominant.,function:Photoreceptor required for image-forming vision at low light intensity. Required for photor
  • Species: Human;Mouse;Rat
  • Range: WB;IHC;IF;ELISA
  • Protein: Rhodopsin
  • DA: 42kD
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