• PAR-3 Polyclonal Antibody
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Upingbio

YP-Ab-13655-100UL

PAR-3 Polyclonal Antibody

PAR-3 Polyclonal Antibody

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  • Gene Name: F2RL2
  • Immunogen: The antiserum was produced against synthesized peptide derived from human F2RL2. AA range:38-87
  • Specificity: PAR-3 Polyclonal Antibody detects endogenous levels of PAR-3 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: F2RL2; PAR3; Proteinase-activated receptor 3; PAR-3; Coagulation factor II receptor-like 2; Thrombin receptor-like 2
  • Background: This gene encodes a member of the protease-activated receptor (PAR) family which is a subfamily of the seven transmembrane G protein-coupled cell surface receptor family. The encoded protein acts as a cofactor in the thrombin-mediated cleavage and activation of the protease-activated receptor family member PAR4. The encoded protein plays an essential role in hemostasis and thrombosis. Alternate splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Feb 2012],
  • Function: function:Receptor for activated thrombin coupled to G proteins that stimulate phosphoinositide hydrolysis.,PTM:A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.,similarity:Belongs to the G-protein coupled receptor 1 family.,subunit:Interacts with INSC/inscuteable and probably GPSM2.,tissue specificity:Highest expression in the megakaryocytes of the bone marrow, lower in mature megakaryocytes, in platelets and in a variety of other tissues such as heart and gut.,
  • Species: Human;Rat;Mouse;
  • Range: IF;ELISA
  • Protein: Proteinase-activated receptor 3
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