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Upingbio
SKU:YP-Ab-13649-1-100UL
Osteoprotegerin Rabbit pAb
Osteoprotegerin Rabbit pAb
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- Gene Name: TNFRSF11B
- Immunogen: Fusion protein of human TNFRSF11B Purification Affinity Purified Conjugation Unconjugated Modification Unmodified Form Liquid
- Dilution ratio: WB: 1/500-1/1000 IHC: 1/50-1/100
- Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
- Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.
- Species: Human;Mouse;Rat
- Range: WB,IHC-P
- DA: Calculated MW: 46 kDa; Observed MW: 46 kDa
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