• MEL-1B-R Polyclonal Antibody
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Upingbio

YP-Ab-13413-100UL

MEL-1B-R Polyclonal Antibody

MEL-1B-R Polyclonal Antibody

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  • Gene Name: MTNR1B
  • Immunogen: The antiserum was produced against synthesized peptide derived from human MTR1B. AA range:301-350
  • Specificity: MEL-1B-R Polyclonal Antibody detects endogenous levels of MEL-1B-R protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000;IHC-p 1:50-300
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: MTNR1B; Melatonin receptor type 1B; Mel-1B-R; Mel1b receptor
  • Background: This gene encodes one of two high affinity forms of a receptor for melatonin, the primary hormone secreted by the pineal gland. This gene product is an integral membrane protein that is a G-protein coupled, 7-transmembrane receptor. It is found primarily in the retina and brain although this detection requires RT-PCR. It is thought to participate in light-dependent functions in the retina and may be involved in the neurobiological effects of melatonin. [provided by RefSeq, Jul 2008],
  • Function: function:High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.,online information:Melatonin receptor entry,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Expressed in retina and less in brain and hippocampus.,
  • Species: Human;Rat;Mouse;
  • Range: WB;IHC
  • Protein: Melatonin receptor type 1B
  • DA: 40kD
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