• GPR56 Polyclonal Antibody
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Upingbio

YP-Ab-13344-100UL

GPR56 Polyclonal Antibody

GPR56 Polyclonal Antibody

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  • Gene Name: GPR56
  • Immunogen: The antiserum was produced against synthesized peptide derived from human GPR56. AA range:251-300
  • Specificity: GPR56 Polyclonal Antibody detects endogenous levels of GPR56 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: GPR56; TM7LN4; TM7XN1; G-protein coupled receptor 56; Protein TM7XN1
  • Background: This gene encodes a member of the G protein-coupled receptor family and regulates brain cortical patterning. The encoded protein binds specifically to transglutaminase 2, a component of tissue and tumor stroma implicated as an inhibitor of tumor progression. Mutations in this gene are associated with a brain malformation known as bilateral frontoparietal polymicrogyria. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2014],
  • Function: disease:Defects in GPR56 are the cause of bilateral frontoparietal polymicrogyria (BFPP) [MIM:606854]. BFPP is characterized by disorganized cortical lamination that is most severe in frontal cortex.,function:Could be involved in cell-cell interactions.,similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.,similarity:Contains 1 GPS domain.,tissue specificity:Widely distributed with highest levels found in thyroid gland, brain and heart. Expressed in a great number of tumor cells.,
  • Species: Human;Rat;Mouse;
  • Range: WB;IF;ELISA
  • Protein: G-protein coupled receptor 56
  • DA: 78kD
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