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Upingbio
SKU:YP-Ab-13249-100UL
FPR1 Polyclonal Antibody
FPR1 Polyclonal Antibody
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- Gene Name: FPR1
- Immunogen: The antiserum was produced against synthesized peptide derived from human FPR1. AA range:155-204
- Specificity: FPR1 Polyclonal Antibody detects endogenous levels of FPR1 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: FPR1; fMet-Leu-Phe receptor; fMLP receptor; N-formyl peptide receptor; FPR; N-formylpeptide chemoattractant receptor
- Background: formyl peptide receptor 1(FPR1) Homo sapiens This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.[provided by RefSeq, Jul 2010],
- Function: function:High affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system.,PTM:Phosphorylated; which is necessary for desensitization.,similarity:Belongs to the G-protein coupled receptor 1 family.,tissue specificity:Neutrophils.,
- Species: Human;Rat;Mouse;
- Range: WB;IHC;IF;ELISA
- Protein: fMet-Leu-Phe receptor
- DA: 40kD
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