• EphA1 Monoclonal Antibody
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Upingbio

YP-Ab-12904-53UL

EphA1 Monoclonal Antibody

EphA1 Monoclonal Antibody

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  • Reaction species: Human
  • Gene Name: EPHA1
  • Protein name: Ephrin type-A receptor 1
  • Immunogen: Purified recombinant fragment of EphA1 expressed in E. Coli.
  • Specificity: EphA1 Monoclonal Antibody detects endogenous levels of EphA1 protein.
  • Composition: Purified antibody in PBS containing 0.03% sodium azide.
  • Source: Monoclonal, Mouse
  • Dilution ratio: WB: 1/500 - 1/2000. IHC: 1/200 - 1/1000. ELISA: 1/10000.. IF 1:50-200
  • Purification process: Affinity purification
  • Concentration: mg/ml
  • Storage: -20°C/1 year
  • Other Names: EPHA1; EPH; EPHT; EPHT1; Ephrin type-A receptor 1; hEpha1; EPH tyrosine kinase; EPH tyrosine kinase 1; Erythropoietin-producing hepatoma receptor; Tyrosine-protein kinase receptor EPH
  • Background: This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis. [provided by RefSeq, Jul 2008],
  • Function: catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.,function:Receptor for members of the ephrin-A family. Binds with a low affinity to ephrin-A1.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family.,similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SAM (sterile alpha motif) domain.,similarity:Contains 2 fibronectin type-III domains.,tissue specificity:Overexpressed in several carcinomas.,
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