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Upingbio
SKU:YP-Ab-12855-100UL
Neuropilin-2 Polyclonal Antibody
Neuropilin-2 Polyclonal Antibody
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- Gene Name: NRP2
- Immunogen: The antiserum was produced against synthesized peptide derived from the Internal region of human NRP2. AA range:791-840
- Specificity: Neuropilin-2 Polyclonal Antibody detects endogenous levels of Neuropilin-2 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000.. IF 1:50-200
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: NRP2; VEGF165R2; Neuropilin-2; Vascular endothelial cell growth factor 165 receptor 2
- Background: This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],
- Function: function:High affinity receptor for semaphorins 3C, 3F, VEGF-165 and VEGF-145 isoforms of VEGF, and the PLGF-2 isoform of PGF.,similarity:Belongs to the neuropilin family.,similarity:Contains 1 MAM domain.,similarity:Contains 2 CUB domains.,similarity:Contains 2 F5/8 type C domains.,subunit:Heterodimer with NRP1 (Probable). Binds PLXNB1.,
- Species: Human;Mouse;Rat
- Range: WB;IHC;IF;ELISA
- Protein: Neuropilin-2
- DA: 100kD
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