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Upingbio
SKU:YP-Ab-12811-100UL
SR-1B Polyclonal Antibody
SR-1B Polyclonal Antibody
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- Gene Name: HTR1B
- Immunogen: The antiserum was produced against synthesized peptide derived from human 5-HT-1B. AA range:201-250
- Specificity: SR-1B Polyclonal Antibody detects endogenous levels of SR-1B protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: HTR1B; HTR1DB; 5-hydroxytryptamine receptor 1B; 5-HT-1B; 5-HT1B; S12; Serotonin 1D beta receptor; 5-HT-1D-beta; Serotonin receptor 1B
- Background: The protein encoded by this intronless gene is a G-protein coupled receptor for serotonin (5-hydroxytryptamine). Ligand binding activates second messengers that inhibit the activity of adenylate cyclase and manage the release of serotonin, dopamine, and acetylcholine in the brain. The encoded protein may be involved in several neuropsychiatric disorders and therefore is often a target of antidepressant and other psychotherapeutic drugs. [provided by RefSeq, Nov 2015],
- Function: function:This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.,PTM:Palmitoylated.,PTM:Phosphorylated. Desensitization of the receptor may be mediated by its phosphorylation.,similarity:Belongs to the G-protein coupled receptor 1 family.,
- Species: Human;Mouse;Rat
- Range: WB;IHC;IF;ELISA
- Protein: 5-hydroxytryptamine receptor 1B
- DA: 43kD
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