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SKU:YP-Ab-12757-100UL
Neurocalcin δ Polyclonal Antibody
Neurocalcin δ Polyclonal Antibody
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- Gene Name: NCALD
- Immunogen: Synthesized peptide derived from Neurocalcin δ . at AA range: 370-450
- Specificity: Neurocalcin δ Polyclonal Antibody detects endogenous levels of Neurocalcin δ protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: IHC: 1/100 - 1/300. ELISA: 1/20000.. IF 1:50-200
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: NCALD; Neurocalcin-delta
- Background: This gene encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of this gene have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined. [provided by RefSeq, Jul 2008],
- Function: function:May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds three calcium ions.,similarity:Belongs to the recoverin family.,similarity:Contains 4 EF-hand domains.,tissue specificity:Retina, cerebrum, cerebellum, brain stem, spinal cord, testis, ovary and small intestine.,
- Species: Human;Mouse;Rat
- Range: IHC;IF;ELISA
- Protein: Neurocalcin-delta
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