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Upingbio

SKU:YP-Ab-12743-100UL

mAChR M5 Polyclonal Antibody

mAChR M5 Polyclonal Antibody

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  • Gene Name: CHRM5
  • Immunogen: The antiserum was produced against synthesized peptide derived from human CHRM5. AA range:281-330
  • Specificity: mAChR M5 Polyclonal Antibody detects endogenous levels of mAChR M5 protein.
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: CHRM5; Muscarinic acetylcholine receptor M5
  • Background: The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The clinical implications of this receptor are unknown; however, stimulation of this receptor is known to increase cyclic AMP levels. [provided by RefSeq, Jul 2008],
  • Function: function:The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.,similarity:Belongs to the G-protein coupled receptor 1 family.,
  • Species: Human;Rat;Mouse;
  • Range: WB;IF;ELISA
  • Protein: Muscarinic acetylcholine receptor M5
  • DA: 60kD
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