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Upingbio
SKU:YP-Ab-12724-100UL
GABA T-3 Polyclonal Antibody
GABA T-3 Polyclonal Antibody
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- Gene Name: SLC6A11
- Immunogen: Synthesized peptide derived from GABA T-3 . at AA range: 370-450
- Specificity: GABA T-3 Polyclonal Antibody detects endogenous levels of GABA T-3 protein.
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
- Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Other Names: SLC6A11; GABT3; GAT3; Sodium- and chloride-dependent GABA transporter 3; GAT-3; Solute carrier family 6 member 11
- Background: The protein encoded by this gene is a sodium-dependent transporter that uptakes gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, which ends the GABA neurotransmission. Defects in this gene may result in epilepsy, behavioral problems, or intellectual problems. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015],
- Function: function:Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.,similarity:Belongs to the sodium:neurotransmitter symporter (SNF) family.,tissue specificity:Widespread distribution in the brain.,
- Species: Human;Mouse;Rat
- Range: WB;ELISA
- Protein: Sodium- and chloride-dependent GABA transporter 3
- DA: 70kD
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