• GAP43 Polyclonal Antibody
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Upingbio

YP-Ab-12630-100UL

GAP43 Polyclonal Antibody

GAP43 Polyclonal Antibody

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  • Gene Name: GAP43
  • Immunogen: Recombinant Protein of Neuromodulin
  • Specificity: The antibody detects endogenous GAP43 protein.
  • Composition: PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB: 1:1000-3000
  • Purification process: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.
  • Storage: -20°C/1 year
  • Other Names: GAP43; Neuromodulin; Axonal membrane protein GAP-43; Growth-associated protein 43; Neural phosphoprotein B-50; pp46
  • Background: The protein encoded by this gene has been termed a 'growth' or 'plasticity' protein because it is expressed at high levels in neuronal growth cones during development and axonal regeneration. This protein is considered a crucial component of an effective regenerative response in the nervous system. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
  • Function: function:This protein is associated with nerve growth. It is a major component of the motile "growth cones" that form the tips of elongating axons.,online information:Gap-43 entry,PTM:Phosphorylation of this protein by a protein kinase C is specifically correlated with certain forms of synaptic plasticity.,similarity:Belongs to the neuromodulin family.,similarity:Contains 1 IQ domain.,subcellular location:Cytoplasmic surface of growth cone and synaptic plasma membranes.,subunit:Binds calmodulin with a greater affinity in the absence of Ca(2+) than in its presence.,
  • Species: Human;Mouse;Rat
  • Range: WB
  • Protein: Neuromodulin
  • DA: 38,43kD
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