• IL1RA rabbit pAb
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YP-Ab-12427-100UL

IL1RA rabbit pAb

IL1RA rabbit pAb

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  • Gene Name: IL1RN IL1F3 IL1RA
  • Immunogen: Synthesized peptide derived from human IL1RA
  • Specificity: This antibody detects endogenous levels of Human IL1RA
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:1000-2000 ELISA 1:5000-20000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Other Names: Interleukin-1 receptor antagonist protein (IL-1RN;IL-1ra;IRAP;ICIL-1RA;IL1 inhibitor;Anakinra)
  • Background: disease:Genetic variation in IL1RN is associated with susceptibility to diabetic nephropathy [MIM:612628]; also called susceptibility to microvascular complications of diabetes type 4 (MVCD4). Diabetic nephropathy is a kidney disease and resultant kidney function impairment due to the long standing effects of diabetes on the microvasculature (glomerulus) of the kidney. Features include increased urine protein and declining kidney function.,function:Inhibits the activity of IL-1 by binding to its receptor. Has no IL-1 like activity.,online information:Interleukin-1 entry,online information:The Singapore human mutation and polymorphism database,pharmaceutical:Available under the name Kineret (Amgen). Used for the reduction in signs and symptoms and slowing the progression of structural damage in moderately to severely active rheumatoid arthritis.,similarity:Belongs to the IL-1 family.,tissue specificity:The intracellular form of IL1RN is predominantly expressed in epithelial cells.,
  • Function: defense response, inflammatory response, immune response, response to wounding, response to endogenous stimulus, response to hormone stimulus, response to organic substance, response to corticosteroid stimulus,response to steroid hormone stimulus, response to glucocorticoid stimulus,
  • Species: Human;Rat;Mouse;
  • Range: WB; ELISA
  • Protein: IL1RA
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