• MTMRC rabbit pAb
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Upingbio

YP-Ab-12399-100UL

MTMRC rabbit pAb

MTMRC rabbit pAb

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  • Gene Name: MTMR12 KIAA1682 PIP3AP
  • Immunogen: Synthesized peptide derived from human MTMRC AA range: 523-573
  • Specificity: This antibody detects endogenous levels of MTMRC at Human/Mouse/Rat
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: Phosphatidylinositide 3-kinase-derived membrane-anchored phosphatidylinositides, such as phosphatidylinositol 3-phosphate (PtdIns(3)P), regulate diverse cellular processes. The protein encoded by this gene functions as an adaptor subunit in a complex with an active PtdIns(3)P 3-phosphatase. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014],
  • Function: caution:Lacks the phosphocysteine intermediate Cys active site in position 391 that is replaced by a Glu residue, preventing the hydrolase activity.,function:Inactive phosphatase that plays a role as an adapter for the phosphatase myotubularin to regulate myotubularin intracellular location.,miscellaneous:Catalytically inactive phosphatase.,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily.,similarity:Contains 1 myotubularin phosphatase domain.,subcellular location:Localizes to punctate vesicles when associated with MTM1.,subunit:Interacts with myotubularin MTM1 and myotubularin-related MTMR2.,tissue specificity:Ubiquitous with prominent expression in brain, heart, kidney, placenta, and lung.,
  • Species: Human; Mouse;Rat
  • Range: WB;ELISA;IHC
  • Protein: MTMRC
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