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Upingbio
SKU:YP-Ab-12165-100UL
RFX6 rabbit pAb
RFX6 rabbit pAb
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- Gene Name: RFX6 RFXDC1
- Immunogen: Synthesized peptide derived from human RFX6 AA range: 264-314
- Specificity: This antibody detects endogenous levels of RFX6 at Human/Mouse
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: The nuclear protein encoded by this gene is a member of the regulatory factor X (RFX) family of transcription factors. Studies in mice suggest that this gene is specifically required for the differentiation of islet cells for the production of insulin, but not for the differentiation of pancreatic polypeptide-producing cells. It regulates the transcription factors involved in beta-cell maturation and function, thus, restricting the expression of the beta-cell differentiation and specification genes. Mutations in this gene are associated with Mitchell-Riley syndrome, which is characterized by neonatal diabetes with pancreatic hypoplasia, duodenal and jejunal atresia, and gall bladder agenesis.[provided by RefSeq, Sep 2010],
- Function: similarity:Belongs to the RFX family.,
- Species: Human; Mouse
- Range: WB;ELISA;IHC
- Protein: RFX6
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