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Upingbio

SKU:YP-Ab-12157-100UL

GLYM rabbit pAb

GLYM rabbit pAb

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  • Gene Name: SHMT2
  • Immunogen: Synthesized peptide derived from human GLYM AA range: 122-172
  • Specificity: This antibody detects endogenous levels of GLYM at Human
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. The encoded product is primarily responsible for glycine synthesis. The activity of the encoded protein has been suggested to be the primary source of intracellular glycine. The gene which encodes the cytosolic form of this enzyme is located on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],
  • Function: catalytic activity:5,10-methylenetetrahydrofolate + glycine + H(2)O = tetrahydrofolate + L-serine.,cofactor:Pyridoxal phosphate.,function:Interconversion of serine and glycine.,miscellaneous:In eukaryotes there are two forms of the enzymes: a cytosolic one and a mitochondrial one.,pathway:One-carbon metabolism; tetrahydrofolate pathway.,similarity:Belongs to the SHMT family.,subunit:Homotetramer.,
  • Species: Human;Rat;Mouse;
  • Range: WB
  • Protein: GLYM
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