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Upingbio
SKU:YP-Ab-12141-100UL
TMPS2 rabbit pAb
TMPS2 rabbit pAb
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- Gene Name: TMPRSS2 PRSS10
- Immunogen: Synthesized peptide derived from human TMPS2 AA range: 98-148
- Specificity: This antibody detects endogenous levels of TMPS2 at Human/Mouse
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008],
- Function: similarity:Belongs to the peptidase S1 family.,similarity:Contains 1 LDL-receptor class A domain.,similarity:Contains 1 peptidase S1 domain.,similarity:Contains 1 SRCR domain.,subcellular location:Activated by cleavage and secreted.,tissue specificity:Expressed strongly in small intestine. Also expressed in prostate, colon, stomach and salivary gland.,
- Species: Human; Mouse
- Range: WB
- Protein: TMPS2
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