• STON2 rabbit pAb
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YP-Ab-12008-100UL

STON2 rabbit pAb

STON2 rabbit pAb

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  • Gene Name: STON2 STN2 STNB
  • Immunogen: Synthesized peptide derived from human STON2 AA range: 47-97
  • Specificity: This antibody detects endogenous levels of STON2 at Human/Mouse
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000; IF/ICC 1:50-200;ELISA 1:2000-20000;IHC-p 1:50-200
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: This gene encodes a protein which is a membrane protein involved in regulating endocytotic complexes. The protein product is described as one of the clathrin-associated sorting proteins, adaptor molecules which ensure specific proteins are internalized. The encoded protein has also been shown to participate in synaptic vesicle recycling through interaction with synaptotagmin 1 required for neurotransmission. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012],
  • Function: domain:The Asn-Pro-Phe (NPF) motifs, which are found in proteins involved in the endocytic pathway, mediate the interaction with the EH domain of SYT1, SYT2, EPS15, EPS15R and ITSN1.,function:Adapter protein involved in endocytic machinery. May be involved in the vesicle recycling. May facilitate clathrin-coated vesicle uncoating.,similarity:Belongs to the Stoned B family.,similarity:Contains 1 MHD (mu homology) domain.,similarity:Contains 1 SHD (stonin homology) domain.,subcellular location:Some fraction is membrane-associated.,subunit:Interacts with the second C2 domain of synaptotagmins SYT1 and SYT2. Interacts with EPS15, EPS15R and ITSN1. Interacts indirectly with the AP-2 adapter complex.,tissue specificity:Ubiquitous.,
  • Species: Human; Mouse
  • Range: WB;IF;FCM;ELISA;IHC
  • Protein: STON2
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