• PSDE rabbit pAb
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Upingbio

YP-Ab-11968-100UL

PSDE rabbit pAb

PSDE rabbit pAb

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  • Gene Name: PSMD14 POH1
  • Immunogen: Synthesized peptide derived from human PSDE AA range: 152-202
  • Specificity: This antibody detects endogenous levels of PSDE at Human/Mouse
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000;IHC-p 1:50-300
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: This gene encodes a component of the 26S proteasome. The 26S proteasome is a large multiprotein complex that catalyzes the degradation of ubiquitinated intracellular proteins. The encoded protein is a component of the 19S regulatory cap complex of the 26S proteasome and mediates substrate deubiquitination. A pseudogene of this gene is also located on the long arm of chromosome 2. [provided by RefSeq, Feb 2012],
  • Function: catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,function:Metalloprotease component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains. The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The function of the 'Lys-63'-specific deubiquitination of the proteasome is unclear.,similarity:Belongs to the peptidase M67A family. PSMD14 subfamily.,similarity:Contains 1 MPN (JAB/Mov34) domain.,subunit:Component of the 19S regulatory cap of the 26S proteasome.,tissue specificity:Widely expressed. Highest levels in heart and skeletal muscle.,
  • Species: Human; Mouse
  • Range: WB;IHC
  • Protein: PSDE
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