• TYW2 rabbit pAb
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Upingbio

YP-Ab-11966-100UL

TYW2 rabbit pAb

TYW2 rabbit pAb

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  • Gene Name: TRMT12 TRM12 TYW2
  • Immunogen: Synthesized peptide derived from human TYW2 AA range: 11-61
  • Specificity: This antibody detects endogenous levels of TYW2 at Human/Mouse/Rat
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1：500-2000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TRMT12 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).[supplied by OMIM, Mar 2008],
  • Function: function:Probable S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wybutosine biosynthesis pathway. Wybutosine is a hyper modified guanosine with a tricyclic base found at the 3'-position adjacent to the anticodon of eukaryotic phenylalanine tRNA.,pathway:tRNA modification; wybutosine-tRNA(Phe) biosynthesis.,sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 371.,sequence caution:Translation N-terminally shortened.,similarity:Belongs to the RNA methyltransferase trmD family. TYW2 subfamily.,
  • Species: Human; Mouse;Rat
  • Range: WB
  • Protein: TYW2
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