• RUVB1 rabbit pAb
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Upingbio

YP-Ab-11964-100UL

RUVB1 rabbit pAb

RUVB1 rabbit pAb

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  • Gene Name: RUVBL1 INO80H NMP238 TIP49 TIP49A
  • Immunogen: Synthesized peptide derived from human RUVB1 AA range: 195-245
  • Specificity: This antibody detects endogenous levels of RUVB1 at Human/Mouse/Rat
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1：500-2000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: This gene encodes a protein that has both DNA-dependent ATPase and DNA helicase activities and belongs to the ATPases associated with diverse cellular activities (AAA+) protein family. The encoded protein associates with several multisubunit transcriptional complexes and with protein complexes involved in both ATP-dependent remodeling and histone modification. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
  • Function: domain:Binding to MYC is dependent on a Myc domain essential for oncogenic activity.,function:Essential for cell proliferation.,function:May be able to bind plasminogen at cell surface and enhance plasminogen activation.,function:Possesses single-stranded DNA-stimulated ATPase and ATP-dependent DNA helicase (3' to 5') activity. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence,
  • Species: Human; Mouse;Rat
  • Range: WB
  • Protein: RUVB1
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