• ROP1A rabbit pAb
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Upingbio

YP-Ab-11818-100UL

ROP1A rabbit pAb

ROP1A rabbit pAb

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  • Gene Name: ROPN1 ROPN1A
  • Immunogen: Synthesized peptide derived from human ROP1A AA range: 85-135
  • Specificity: This antibody detects endogenous levels of ROP1A at Human
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000;IHC-p 1:50-300
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: The protein encoded by this gene is found in the fibrous sheath of spermatazoa, where it interacts with rhophilin, a Rho GTPase binding protein. The encoded protein also can bind an A-kinase anchoring protein (AKAP110) and a calcium-binding tyrosine phosphorylation-regulated protein (CABYR). This protein may be involved in sperm motility and has been shown to be a cancer-testis antigen in hematologic malignancies. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene. [provided by RefSeq, Dec 2015],
  • Function: developmental stage:Expressed in fetal liver.,domain:The RIIa domain mediates interaction with AKAP3.,miscellaneous:The name 'ropporin' comes from the Japanese word 'oppo' which means 'tail'.,similarity:Belongs to the ropporin family.,similarity:Contains 1 RIIa domain.,subcellular location:In the sperm tail, found in the principal piece and in the cytoplasmic droplet located at the distal end of the midpiece. Inner surface of the fibrous sheath.,subunit:Homodimer. Interacts with AKAP3 and RHPN1 (By similarity). May interact with SPA17.,tissue specificity:Testis specific in adult. Overexpressed in hematologic tumor cells.,
  • Species: Human;Rat;Mouse;
  • Range: WB;IHC
  • Protein: ROP1A
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