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SKU:YP-Ab-11788-100UL
ZMYM3 rabbit pAb
ZMYM3 rabbit pAb
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- Gene Name: ZMYM3 DXS6673E KIAA0385 ZNF261
- Immunogen: Synthesized peptide derived from human ZMYM3 AA range: 258-308
- Specificity: This antibody detects endogenous levels of ZMYM3 at Human/Mouse
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: This gene is located on the X chromosome and is subject to X inactivation. It is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X;13) involving this gene is associated with X-linked mental retardation. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2010],
- Function: disease:A chromosomal aberration involving ZMYM3 may be a cause of X-linked mental retardation in Xq13.1. Translocation t(X;13)(q13.1;?).,similarity:Contains 9 MYM-type zinc fingers.,subunit:May be a component of a BHC histone deacetylase complex that contains HDAC1, HDAC2, HMG20B/BRAF35, AOF2/LSD1, RCOR1/CoREST, PHF21A/BHC80, ZMYM2, ZNF217, ZMYM3, GSE1 and GTF2I.,tissue specificity:Most abundant in brain, moderate in muscle and heart, low in other tissues except placenta.,
- Species: Human; Mouse
- Range: WB
- Protein: ZMYM3
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