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Upingbio
SKU:YP-Ab-11778-100UL
TCEA1 rabbit pAb
TCEA1 rabbit pAb
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- Gene Name: TCEA1 GTF2S TFIIS
- Immunogen: Synthesized peptide derived from human TCEA1 AA range: 50-100
- Specificity: This antibody detects endogenous levels of TCEA1 at Human/Mouse/Rat
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1：500-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Function: alternative products:Additional isoforms seem to exist,disease:A chromosomal rearrangement involving TCEA1 may be a cause of salivary gland pleiomorphic adenomas (PA) [181030]. Pleiomorphic adenomas are the most common benign epithelial tumors of the salivary gland. Translocation t(3;8)(p21;q12) with PLAG1.,function:Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.,miscellaneous:S-II binds to RNA-polymerase II in the absence of transcription.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the TFS-II family.,similarity:Contains 1 TFIIS
- Species: Human; Mouse;Rat
- Range: WB
- Protein: TCEA1
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