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Upingbio
SKU:YP-Ab-11705-100UL
NH2L1 rabbit pAb
NH2L1 rabbit pAb
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- Gene Name: NHP2L1
- Immunogen: Synthesized peptide derived from human NH2L1 AA range: 33-83
- Specificity: This antibody detects endogenous levels of NH2L1 at Human/Mouse/Rat
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1：500-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: Originally named because of its sequence similarity to the Saccharomyces cerevisiae NHP2 (non-histone protein 2), this protein appears to be a highly conserved nuclear protein that is a component of the [U4/U6.U5] tri-snRNP. It binds to the 5' stem-loop of U4 snRNA. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008],
- Function: function:Binds to the 5'-stem-loop of U4 snRNA and may play a role in the late stage of spliceosome assembly. The protein undergoes a conformational change upon RNA-binding.,similarity:Belongs to the ribosomal protein L7Ae family.,subcellular location:Concentrated in the dense fibrillar component of the nucleolus.,subunit:Interacts with RAD17.,tissue specificity:Ubiquitous.,
- Species: Human; Mouse;Rat
- Range: WB
- Protein: NH2L1
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