1
/
of
1
Upingbio
SKU:YP-Ab-11636-100UL
TFB2M rabbit pAb
TFB2M rabbit pAb
Regular price
$0.00 USD
Regular price
Sale price
$0.00 USD
Unit price
/
per
Shipping calculated at checkout.
Couldn't load pickup availability
- Gene Name: TFB2M NS5ATP5
- Immunogen: Synthesized peptide derived from human TFB2M AA range: 192-242
- Specificity: This antibody detects endogenous levels of TFB2M at Human/Mouse/Rat
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1：500-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Function: function:S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.,induction:By the nuclear respiratory factors NRF1 and NRF2/GABPB2 and PGC-1 coactivators.,similarity:Belongs to the rRNA adenine N(6)-methyltransferase family. KsgA subfamily.,subunit:Interacts with mitochondrial RNA polymerase POLRMT. Interacts with TFAM.,tissue specificity:Ubiquitously expressed.,
- Species: Human; Mouse;Rat
- Range: WB
- Protein: TFB2M
Share
