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Upingbio
SKU:YP-Ab-11604-100UL
SNX17 rabbit pAb
SNX17 rabbit pAb
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- Gene Name: SNX17 KIAA0064
- Immunogen: Synthesized peptide derived from human SNX17 AA range: 398-448
- Specificity: This antibody detects endogenous levels of SNX17 at Human/Mouse/Rat
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000;IHC-p 1:50-300
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members, but contains a B41 domain. This protein interacts with the cytoplasmic domain of P-selectin, and may function in the intracellular trafficking of P-selectin. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2012],
- Function: domain:The PX domain is required for association with endosomes.,function:May be involved in protein trafficking.,similarity:Belongs to the sorting nexin family.,similarity:Contains 1 PX (phox homology) domain.,similarity:Contains 1 Ras-associating domain.,subcellular location:Associated with early endosomes.,subunit:Interacts with the C-termini of P-selectin, PTC, LDLR, VLDLR, LRP1 and LRP8.,
- Species: Human; Mouse;Rat
- Range: WB;IHC
- Protein: SNX17
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