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Upingbio
SKU:YP-Ab-11548-100UL
KR105 rabbit pAb
KR105 rabbit pAb
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- Gene Name: KRTAP10-5 KAP10.5 KAP18-5 KRTAP10.5 KRTAP18-5 KRTAP18.5
- Immunogen: Synthesized peptide derived from human KR105 AA range: 88-138
- Specificity: This antibody detects endogenous levels of KR105 at Human
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: This is an intronless gene located in a cluster of related genes on the q arm of chromosome 21. The proteins encoded by these genes form disulfide bonds with cysteine residues in hair keratins, thereby contributing to the structure and stability of hair fibers. [provided by RefSeq, Apr 2014],
- Function: function:In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins.,similarity:Belongs to the KRTAP type 10 family.,subunit:Interacts with hair keratins.,tissue specificity:Restricted to a narrow region of the hair fibre cuticle, lying approximately 20 cell layers above the apex of the dermal papilla of the hair root; not detected in any other tissues.,
- Species: Human;Rat;Mouse;
- Range: WB;ELISA;IHC
- Protein: KR105
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