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Upingbio
SKU:YP-Ab-11522-100UL
TRM6 rabbit pAb
TRM6 rabbit pAb
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- Gene Name: TRMT6 KIAA1153 TRM6 CGI-09
- Immunogen: Synthesized peptide derived from human TRM6 AA range: 175-225
- Specificity: This antibody detects endogenous levels of TRM6 at Human/Mouse
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: This gene encodes a member of the tRNA methyltransferase 6 protein family. A similar protein in yeast is part of a two component methyltransferase, which is involved in the posttranslational modification that produces the modified nucleoside 1-methyladenosine in tRNAs. Modified 1-methyladenosine influences initiator methionine stability and may be involved in the replication of human immunodeficiency virus type 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
- Function: function:Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the TRM6/GCD10 family.,subunit:tRNA (adenine-N(1)-)-methyltransferase is a heterodimer of trm6 and trm61.,tissue specificity:Expressed in brain, liver, testis and ovary.,
- Species: Human; Mouse
- Range: WB
- Protein: TRM6
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