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Upingbio
SKU:YP-Ab-11385-100UL
RT4I1 rabbit pAb
RT4I1 rabbit pAb
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- Gene Name: RTN4IP1 NIMP
- Immunogen: Synthesized peptide derived from human RT4I1 AA range: 282-332
- Specificity: This antibody detects endogenous levels of RT4I1 at Human/Mouse
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1：500-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: This gene encodes a mitochondrial protein that interacts with reticulon 4, which is a potent inhibitor of regeneration following spinal cord injury. This interaction may be important for reticulon-induced inhibition of neurite growth. Mutations in this gene can cause optic atrophy 10, with or without ataxia, mental retardation, and seizures. There is a pseudogene for this gene on chromosome 12. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016],
- Function: function:Appears to be a potent inhibitor of regeneration following spinal cord injury.,similarity:Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.,subunit:Interacts with RTN4, UQCRC1 and UQCRC2.,tissue specificity:Widely expressed in mitochondria-enriched tissues. Found in heart, muscle, kidney, liver, brain and placenta.,
- Species: Human; Mouse
- Range: WB
- Protein: RT4I1
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