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Upingbio
SKU:YP-Ab-11366-100UL
FBX6 rabbit pAb
FBX6 rabbit pAb
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- Gene Name: FBXO6 FBG2 FBS2 FBX6
- Immunogen: Synthesized peptide derived from human FBX6 AA range: 30-80
- Specificity: This antibody detects endogenous levels of FBX6 at Human/Mouse/Rat
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class, and its C-terminal region is highly similar to that of rat NFB42 (neural F Box 42 kDa) which may be involved in the control of the cell cycle. [provided by RefSeq, Jul 2008],
- Function: function:Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation.,online information:hFBG2,similarity:Contains 1 F-box domain.,similarity:Contains 1 FBA (F-box associated) domain.,subunit:Part of a SCF (SKP1-cullin-F-box) protein ligase complex.,
- Species: Human; Mouse;Rat
- Range: WB
- Protein: FBX6
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