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SKU:YP-Ab-11365-100UL
PTN4 rabbit pAb
PTN4 rabbit pAb
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- Gene Name: PTPN4
- Immunogen: Synthesized peptide derived from human PTN4 AA range: 496-546
- Specificity: This antibody detects endogenous levels of PTN4 at Human/Mouse
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000;IHC-p 1:50-300
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signalling downstream of the glutamate receptors through tyrosine dephosphorylation. [provided by RefSeq, Jul 2008],
- Function: catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,function:May act at junctions between the membrane and the cytoskeleton.,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.,similarity:Contains 1 FERM domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 tyrosine-protein phosphatase domain.,
- Species: Human; Mouse
- Range: WB;IHC
- Protein: PTN4
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