• ARID2 rabbit pAb
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YP-Ab-11340-100UL

ARID2 rabbit pAb

ARID2 rabbit pAb

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  • Gene Name: ARID2 KIAA1557
  • Immunogen: Synthesized peptide derived from human ARID2 AA range: 309-359
  • Specificity: This antibody detects endogenous levels of ARID2 at Human
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1：500-2000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: ARID2 is a subunit of the PBAF chromatin-remodeling complex (see BAF180; MIM 606083), which facilitates ligand-dependent transcriptional activation by nuclear receptors (Yan et al., 2005 [PubMed 15985610]).[supplied by OMIM, Mar 2008],
  • Function: developmental stage:Up-regulated in adult heart (at protein level).,function:Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). May be involved in targeting the complex to different genes. May be involved in regulating transcriptional activation of cardiac genes.,sequence caution:Differs from position 1094 onward for unknown reason.,similarity:Contains 1 ARID domain.,similarity:Contains 1 C2H2-type zinc finger.,subunit:Component of the SWI/SNF-B (PBAF) chromatin remodeling complex, at least composed of SMARCA4/BRG1, SMARCB1/BAF47, ACTL6A/BAF53A or ACTL6B/BAF53B, SMARCE1/BAF57, SMARCD1/BAF60A, SMARCD2/BAF60B, perhaps SMARCD3/BAF60C, SMARCC1/BAF155, SMARCC2/BAF170, PB1/BAF180, ARID2/BAF200, ARID1A/BAF250A or ARID1B/BAF2
  • Species: Human;Rat;Mouse;
  • Range: WB
  • Protein: ARID2
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