• VP37C rabbit pAb
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Upingbio

YP-Ab-11312-100UL

VP37C rabbit pAb

VP37C rabbit pAb

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  • Gene Name: VPS37C PML39
  • Immunogen: Synthesized peptide derived from human VP37C AA range: 220-270
  • Specificity: This antibody detects endogenous levels of VP37C at Human/Mouse
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1：500-2000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: VPS37C is a subunit of ESCRT-I (endosomal sorting complex required for transport I), a complex in the class E vacuolar protein sorting (VPS) pathway required for sorting ubiquitinated transmembrane proteins into internal vesicles of multivesicular bodies (Eastman et al., 2005 [PubMed 15509564]).[supplied by OMIM, Mar 2008],
  • Function: function:Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation.,similarity:Belongs to the VPS37 family.,similarity:Contains 1 VPS37 C-terminal domain.,subcellular location:Probably associates with membranes. Recruited to the plasma membrane by HIV-1.,subunit:Component of the ESCRT-I complex (endosomal sorting complex required for transport I) which consists of TSG101, VPS28, a VPS37 protein (VPS37A to -D) and a FAM125/MVB12 protein (FAM125A or -B) in a 1:1:1:1 stoechiometry. Interacts with TSG101, VPS28, FAM125A and FAM125B. Interacts with HGS and STAM2. Interacts with CEP55.,
  • Species: Human; Mouse
  • Range: WB
  • Protein: VP37C
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