• TBCD rabbit pAb
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Upingbio

YP-Ab-11290-100UL

TBCD rabbit pAb

TBCD rabbit pAb

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  • Gene Name: TBCD KIAA0988 SSD1 TFCD PP1096
  • Immunogen: Synthesized peptide derived from human TBCD AA range: 419-469
  • Specificity: This antibody detects endogenous levels of TBCD at Human/Mouse
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1：500-2000
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: Cofactor D is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. [provided by RefSeq, Jul 2008],
  • Function: function:Tubulin-folding protein; involved in the first step of the tubulin folding pathway. Modulates microtubule dynamics by capturing GTP-bound beta-tubulin (TUBB).,induction:Down-regulated by shear stress.,similarity:Belongs to the TBCD family.,similarity:Contains 3 HEAT repeats.,subunit:Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.,tissue specificity:Ubiquitously expressed.,
  • Species: Human; Mouse
  • Range: WB
  • Protein: TBCD
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