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Upingbio
SKU:YP-Ab-11286-100UL
ITM2C rabbit pAb
ITM2C rabbit pAb
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- Gene Name: ITM2C BRI3 hucep-14 NPD018 PSEC0047
- Immunogen: Synthesized peptide derived from human ITM2C AA range: 1-51
- Specificity: This antibody detects endogenous levels of ITM2C at Human/Mouse/Rat
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000;IHC-p 1:50-300
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Function: PTM:Type I membrane-bound, as well as soluble, furin has a pre-eminent role in ITM2C proteolytic processing. PCSK7 and PCSK5 may also be involved although to a lesser extent. The soluble form of PCSK7 is incapable of processing ITM2C.,similarity:Belongs to the ITM2 family.,similarity:Contains 1 BRICHOS domain.,subunit:Interacts with BACE1.,tissue specificity:High levels in the brain, specifically in the cerebral cortex, medulla, amygdala, hippocampus, thalamus, caudate nucleus, cerebellum, olfactory lobe and spinal cord. Very low levels in other organs.,
- Species: Human; Mouse;Rat
- Range: WB;IHC
- Protein: ITM2C
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