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SKU:YP-Ab-11214-100UL
PYDC1 rabbit pAb
PYDC1 rabbit pAb
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- Gene Name: PYDC1 ASC2 ASCI POP1 PYC1
- Immunogen: Synthesized peptide derived from human PYDC1 AA range: 25-75
- Specificity: This antibody detects endogenous levels of PYDC1 at Human
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: IHC-p 1：50-200. IF 1:50-200
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Function: function:Associates with apoptosis-associated specklike protein containing a CARD domain (ASC) and modulates its ability to collaborate with pyrin and cryopyrin in NF-kappa-B and pro-caspase-1 activation. Suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS.,PTM:Phosphorylated.,similarity:Contains 1 DAPIN domain.,subunit:Interacts with PYCARD/ASC.,tissue specificity:Predominantly expressed in monocytes, macrophages and granulocytes.,
- Species: Human;Rat;Mouse;
- Range: IHC;IF
- Protein: PYDC1
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