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Upingbio
SKU:YP-Ab-11152-100UL
CNDH2 rabbit pAb
CNDH2 rabbit pAb
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- Gene Name: NCAPH2 CAPH2
- Immunogen: Synthesized peptide derived from human CNDH2 AA range: 501-551
- Specificity: This antibody detects endogenous levels of CNDH2 at Human/Mouse/Rat
- Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
- Source: Polyclonal, Rabbit,IgG
- Dilution ratio: WB 1:500-2000
- Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
- Concentration: 1 mg/ml
- Storage: -20°C/1 year
- Background: This gene encodes one of the non-SMC subunits of the condensin II complex. This complex plays an essential role in mitotic chromosome assembly. Alternate splicing of this gene results in multiple transcript variants.[provided by RefSeq, May 2010],
- Function: function:Regulatory subunit of the condensin-2 complex, a complex that seems to provide chromosomes with an additional level of organization and rigidity and in establishing mitotic chromosome architecture. May play a role in lineage-specific role in T-cell development.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the CND2 H2 (condensin-2 subunit 2) family.,subcellular location:Distributed along the arms of chromosomes assembled in vivo and in vitro.,subunit:Component of the condensin-2 complex, which contains the smc2 and smc4 heterodimer, and three non SMC subunits, ncapg2, ncaph2 and ncapd3 that probably regulate the complex.,
- Species: Human; Mouse;Rat
- Range: WB
- Protein: CNDH2
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