• PDLI3 rabbit pAb
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YP-Ab-11102-100UL

PDLI3 rabbit pAb

PDLI3 rabbit pAb

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  • Gene Name: PDLIM3 ALP
  • Immunogen: Synthesized peptide derived from human PDLI3 AA range: 251-301
  • Specificity: This antibody detects endogenous levels of PDLI3 at Human/Mouse/Rat
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000;IHC-p 1:50-300
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Aberrant alternative splicing of this gene may play a role in myotonic dystrophy. [provided by RefSeq, Apr 2012],
  • Function: disease:Quantitative or qualitative alterations of expression have not been detected in facioscapulohumeral muscular dystrophy (FSHD).,function:May play a role in the organization of actin filament arrays within muscle cells.,similarity:Contains 1 LIM zinc-binding domain.,similarity:Contains 1 PDZ (DHR) domain.,subcellular location:Localizes to myofiber Z-lines.,subunit:Interacts with ACTN2.,tissue specificity:Isoform 1 is highly expressed in differentiated skeletal muscle. Isoform 2 is heart-specific.,
  • Species: Human; Mouse;Rat
  • Range: WB;IHC
  • Protein: PDLI3
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