• KBTBA rabbit pAb
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Upingbio

YP-Ab-11089-100UL

KBTBA rabbit pAb

KBTBA rabbit pAb

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  • Gene Name: KBTBD10 KRP1
  • Immunogen: Synthesized peptide derived from human KBTBA AA range: 268-318
  • Specificity: This antibody detects endogenous levels of KBTBA at Human/Rat
  • Composition: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • Source: Polyclonal, Rabbit,IgG
  • Dilution ratio: WB 1:500-2000;IHC-p 1:50-300
  • Purification process: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
  • Concentration: 1 mg/ml
  • Storage: -20°C/1 year
  • Background: This gene is a member of the kelch-like family. The encoded protein contains a BACK domain, a BTB/POZ domain, and 5 Kelch repeats. This protein is thought to function in skeletal muscle development and maintenance. Mutations in this gene have been associated with nemaline myopathy (NM), a rare congenital muscle disorder. [provided by RefSeq, Mar 2015],
  • Function: function:Required for pseudopod elongation in transformed cells. Substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.,pathway:Protein modification; protein ubiquitination.,PTM:Ubiquitinated and probably targeted for proteasome-independent degradation.,similarity:Contains 1 BTB (POZ) domain.,similarity:Contains 5 Kelch repeats.,subcellular location:Predominantly cytoplasmic but can co-localize with F-actin at the membrane ruffle-like structures at the tips of transformation-specific pseudopodia.,subunit:Interacts with NRAP (By similarity). Part of a complex that contains CUL3, RBX1 and KBTBD10.,tissue specificity:Sarcomeric muscle.,
  • Species: Human;Rat
  • Range: WB;IHC
  • Protein: KBTBA
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